Fluid responsiveness
Conditions
Interventions
Gold Standard:Fluid responsiveness is defined as respiratory variation of aortic blood flow peak velocity of more than 15%.
Sponsors
Peking University First Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Children with elective craniotomy and epilepsy under general anesthesia; 2. Aged 4 to 9 years.
Exclusion criteria
Exclusion criteria: 1. Hemodynamic instability: fluctuations in heart rate and/or systolic blood pressure obviously require inotropic drugs or vasoconstrictors; 2. Obvious arrhythmia; 3. Severe ventricular systolic dysfunction (ejection fraction <50%); 4. Obvious respiratory diseases; 5. The guardian refuses to participate in the trial; 6. Has participated in other clinical studies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| variation of pulse pressure variation;SEN, SPE, ACC, AUC of ROC, PPV, NPV;SEN, SPE, ACC, AUC of ROC, PPV, NPV;SEN, SPE, ACC, AUC of ROC, PPV, NPV; | — |
Secondary
| Measure | Time frame |
|---|---|
| variation of systolic blood pressure; | — |
Countries
China
Contacts
Public ContactSong Linlin
Peking University First Hospital
Outcome results
None listed