Onychomycosis
Conditions
Interventions
Group A:amorofen dissolvable microneedle
Group B:Oral use Itraconazole
Sponsors
Shanghai Skin Disease Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. According to the history, physical signs and laboratory examination, the patients with onychomycosis were diagnosed clinically; 2. Direct microscopic examination and / or fungal culture were positive; 3. Aged >= 18 years, male and female; 4. OSI score 8-10.
Exclusion criteria
Exclusion criteria: 1. Partially exuded or combined with active bacteria or virus infection; 2. Those who suffer from neuropsychiatric diseases or are using other medications that affect the curative effect; 3. Psoriasis patients; 4. Those who have systematically used antifungal agents or have used glucocorticoids systematically within 4 weeks before being selected; 5. Those who have used topical anti-fungal drugs within 2 weeks before being selected; 6. Participate in other drug trials within 30 days before screening.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Onychomycosis Severity Index; | — |
Secondary
| Measure | Time frame |
|---|---|
| Mycological detection; | — |
Countries
China
Contacts
Public ContactTan Jingwen
Shanghai Skin Disease Hospital
Outcome results
None listed