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Correlation study of diffusion kurtosis imaging on motor function and cognitive function in patients with cerebral hemorrhage

Correlation study of diffusion kurtosis imaging on motor function and cognitive function in patients with cerebral hemorrhage

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100046581
Enrollment
Unknown
Registered
2021-05-22
Start date
2021-05-17
Completion date
Unknown
Last updated
2022-01-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cerebral hemorrhage

Interventions

Normal control group:Nil
Cerebral hemorrhage group:Nil

Sponsors

Subei People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Inclusion criteria of the experimental group (1) Be admitted to the hospital within 24 hours of onset; (2) A single basal ganglia hemorrhage was diagnosed according to the 2019 version of the guidelines for diagnosis and treatment of cerebral hemorrhage; (3) There are clear signs of nervous system positioning; (4) Aged 18 to 80 years, estimate the bleeding volume according to Tadas formula, and the bleeding volume is less than 20ml; (5) The patient's vital signs such as lucid consciousness, breathing, and heartbeat are stable, and can effectively cooperate with physical examination, neurological function scale assessment and magnetic resonance examination; (6) All patients were right-handed, agreed and signed an informed consent form. 2. Control group inclusion criteria (1) Have independent behavioral ability, and the nervous system has no abnormalities in physical examination; (2) Aged 18 to 80 years; (3) Agree and be able to complete relevant scales and magnetic resonance examinations; (4) All selected candidates are right-handed, agree and sign an informed consent form.

Exclusion criteria

Exclusion criteria: 1. Exclusion criteria of the experimental group (1) The hematoma ruptures to the cerebral ventricle or subarachnoid space; (2) Past medical history of cerebral hemorrhage, cerebral infarction, central nervous system infection, central nervous system demyelination, etc.; medical history of dementia, depression, or Parkinsons syndrome that can lead to cognitive decline; (3) Cerebral infarction Secondary cerebral hemorrhage caused by aneurysm, arteriovenous malformation or other causes of secondary cerebral hemorrhage; (4) Head MRI showed brain atrophy and deep white matter T2WI high signal (D>1cm); (5) Accompanied by serious infection, liver failure, renal failure, abnormal blood coagulation mechanism, thrombocytopenia, tumor and other diseases. 2. Control group exclusion criteria (1) Past medical history of stroke, traumatic brain injury, etc.; (2) Past dementia, Parkinson's disease and other diseases that may cause cognitive decline; (3) Head MRI showed brain atrophy and deep white matter T2WI high signal (D>1cm); (4) Accompanied by serious infection, liver and kidney failure, abnormal blood coagulation mechanism, thrombocytopenia, tumor and other diseases.

Design outcomes

Primary

MeasureTime frame
Diffusion kurtosis imaging;

Countries

China

Contacts

Public ContactChen Yingzhu

Subei People's Hospital

yzchendr@163.com+86 18051061299

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026