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Value and clinical application of mNGS on differentiation diagnosis of infection and tumor

Value and clinical application of mNGS on differentiation diagnosis of infection and tumor

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100046572
Enrollment
Unknown
Registered
2021-05-22
Start date
2021-06-01
Completion date
Unknown
Last updated
2022-01-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infection and Cancer

Interventions

case series:N/A

Sponsors

Huashan Hospital Affiliated to Fudan University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Aged >= 18 years; 2. There is no restriction on gender; 3. Patients admitted to Huashan Hospital during the period 2021.4.1-2021.8.31 and meet one of the following diagnoses: (1) Classic fever pending investigation: fever lasts for more than 3 weeks, oral temperature exceeds 38.3 ? at least 3 times (or body temperature fluctuates more than 1.2 ? within 1 day at least 3 times), after at least 1 week of outpatient or inpatient condition assessment, it is still not clear diagnosis; (2) Fever of inpatients to be checked: no fever at admission, fever for more than 3 days after admission, oral temperature over 38.3 ? at least 3 times, or body temperature fluctuating over 1.2 ? within 1 day at least 3 times; (3) Fever of agranulocytosis is to be checked: the absolute value of blood neutrophils is less than 0.5x10^9/L; fever exceeds 3 days, oral temperature exceeds 38.3 ? at least 3 times, or body temperature fluctuates more than 1.2 ? within 1 day ; The body fluid specimen was cultured for more than 48 hours and the result was negative. 4. Those who understand and sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Difficulty in obtaining specimens; 2. Pregnant women; 3. Non-infectious fever of known cause.

Design outcomes

Primary

MeasureTime frame
Blood routine;Procalcitonin;liver function;

Countries

China

Contacts

Public ContactWang Minggui

Huashan Hospital Affiliated to Fudan University

mgwang@fudan.edu.cn+86 52888181

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026