traumatic brain injury
Conditions
Interventions
PHI group:NA
Non-PHI group:NA
Sponsors
The First Affiliated Hospital of Wenzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Aged > 18 years; 2. There is a clear history of head trauma, and the presence of brain contusion is confirmed by head CT scan; 3. It is not accompanied by serious damage to other parts of the brain, and the abbreviated injury scale (AIS) score of other parts outside the skull is <= 3 points; 4. The first CT scan of the head is within 6 hours after the injury, and at least one CT scan is performed within 72 hours after admission.
Exclusion criteria
Exclusion criteria: 1. The indications for craniotomy on admission are clearly needed for emergency craniotomy; 2. Take anticoagulant and antiplatelet drugs (warfarin, aspirin, clopidogrel, etc.); 3. Combined with severe liver, spleen, kidney and other organ damage and severe hemorrhagic shock; 4. Open brain injury (such as gunshot wound, sword wound, etc.); 5. Pre-existing diseases such as renal insufficiency and abnormal parathyroid function; intake of drugs or diseases that affect calcium metabolism (such as abnormal parathyroid function, malignant tumors, massive blood transfusion, etc.); 6. Known past brain diseases (traumatic or non-traumatic) accompanied by permanent neurological defects; 7. Known history of autoimmune diseases; 8. Acute or chronic infectious diseases; 9. Pregnancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Demographic data;Clinical data at admission;Imaging parameters at admission;Laboratory indicators at the time of admission; | — |
Countries
China
Contacts
Public ContactZhuge Qichuan
The First Affiliated Hospital of Wenzhou Medical University
Outcome results
None listed