Acute Pancreatitis
Conditions
Interventions
Sponsors
The First Affiliated Hospital of Chongiqng Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients with acute pancreatitis who were hospitalized in the ICU (Intensive Care Unit) of the First Affiliated Hospital of Chongqing Medical University; 2. The diagnosis of acute pancreatitis is based on the 2012 Atlanta revised diagnostic criteria: (1) Pancreatic pain that is acute and radiates to the lower back; (2) Serum amylase and lipase levels are more than 3 times higher than normal levels; (3) In line with the imaging examination of acute pancreatitis. Patients who meet the diagnosis include at least two of the above characteristics. 3. The patient voluntarily signed the informed consent form; 4. Aged 18 to 80 years.
Exclusion criteria
Exclusion criteria: 1. Any surgery performed three days after admission; 2. Past or current use of immunosuppressive agents; 3. Impaired innate immune function; 4. History of tumor or chronic lung disease, kidney disease or cardiovascular disease; 5. Biliary pancreatitis or traumatic pancreatitis; 6. Pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Th17 / CD4 + Ratio;Serum levels of tumor necrosis factor-a (TNF-a), interleukin-1ß (IL-1ß), interleukin-6 (IL-6), interleukin-8 (IL-8), interleukin-10 (IL-10), interleukin-17A (IL-17A) and CXCL1; | — |
Countries
China
Contacts
Public ContactYang Jian
The First Affiliated Hospital of Chongiqng Medical University
Outcome results
None listed