Choledocholithiasis
Conditions
Interventions
Incision group (EST group):Endoscopic sphincterotomy
Expansion group (EPBD group):Endoscopic papillary balloon dilation
Incision combined expansion group (ESBD group):Endoscopic sphincterotomy combined with endoscopic papillary balloon dilation
Sponsors
the First Affiliated Hospital of Nanjing Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.ERCP was used to remove choledocholithiasis before operation; 2.Aged >= 18 years; 3.The subjects voluntarily participated in the trial and signed the informed consent.
Exclusion criteria
Exclusion criteria: 1.Coagulation dysfunction (INR > 1.3); 2.Malignant tumor; 3.Thrombocytopenia (platelet < 50 x 10^9); 4.Taking anticoagulant or antiplatelet drugs; 5.Combined with acute pancreatitis, recurrent history of pancreatitis, chronic pancreatitis; 6.Acute obstructive suppurative cholangitis: those whose infection has been controlled can be included in the group; 7.The diameter of the stones was more than 10 mm and the number of stones was more than 5; 8.ERCP sphincterotomy or dilation was performed in the past; 9.During the operation, it was judged that EST or EPBD was not suitable, such as diverticulum papilla, small papilla, ampulla tumor, digestive tract diversion (after Bi II or total gastrectomy), benign and malignant stricture of common bile duct; 10.Risk factors of PEP related to operation: using pre incision intubation, pancreatic sphincterotomy, guide wire entering pancreatic duct more than once during operation, pancreatic duct development, difficult intubation (intubation time more than 5 minutes, intubation times more than 5 times); 11.Pancreatic duct stents were placed to prevent pep; 12.Incarceration of duodenal papillary stones; 13.Intrahepatic bile duct stones; 14.Cholecystocolonic fistula; 15.Pregnant women; 16.Primary sclerosing cholangitis; 17.Heart, lung or liver failure.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Success rate of one-stage stone extraction;Post-procedure complication; | — |
Secondary
| Measure | Time frame |
|---|---|
| Frequency of use of mechanical lithotripsy;Time of procedure;Total success rate of stone extraction;Total success rate of stone extraction; | — |
Countries
China
Contacts
Public ContactZhu Hong, Xu Shunfu
the First Affiliated Hospital of Nanjing Medical University
Outcome results
None listed