Hyponatremia
Conditions
Interventions
Experimental group:Isotonic solution (acetic acid electrolyte balance solution)
Control group:Hypotonic solution (pediatric Electrolyte supplements injection)
Sponsors
Peking University First Hospital
Eligibility
Sex/Gender
All
Age
No minimum to 6 Years
Inclusion criteria
Inclusion criteria: Children aged 0 to 6 years undergoing elective intracranial epileptic foci excision under general anesthesia.
Exclusion criteria
Exclusion criteria: 1.Hyponatremia (serum natrium 155 mmol/L) preoperatively; 2.Operation duration < 30min; 3.Significant cardiovascular diseases; 4.Significant respiratory diseases; 5.Severe intracranial hypertension; 6.Refusal to participation by patients' guardians; 7.Already participated in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Poor serum sodium concentration; | — |
Secondary
| Measure | Time frame |
|---|---|
| Change of sodium ion level ;Incidence of hyponatremia and hyperchloremia;Changes of potassium ion, chloride ion, pH and alkali residue at each postoperative observation point compared with that before surgery;Brain relaxation score; | — |
Countries
China
Contacts
Public ContactSong Linlin
Peking University First Hospital
Outcome results
None listed