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To retrospectively analyze and evaluate the efficacy and safety of PD-1 inhibitor combined with paclitaxel-platinum chemotherapy in the treatment of recurrent/metastatic/refractory cervical cancer

To retrospectively analyze and evaluate the efficacy and safety of PD-1 inhibitor combined with paclitaxel-platinum chemotherapy in the treatment of recurrent/metastatic/refractory cervical cancer

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100046526
Enrollment
Unknown
Registered
2021-05-21
Start date
2021-06-01
Completion date
Unknown
Last updated
2022-01-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Recurrent/metastatic/refractory cervical cancer

Interventions

Case series:None

Sponsors

the First Affiliated Hospital of Zhengzhou University
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: 1.Cervical malignancy confirmed by pathology in our hospital; 2.Have received at least first-line or above platinum-containing standard chemotherapy; 3.After disease recurrence and metastasis were confirmed by pathology in our hospital or residual and persistent lesions were confirmed by imaging, "PD-1 inhibitor combined with paclitaxel-platinum" comprehensive treatment regimen was applied for at least 4 cycles; 4.Complete imaging data before and after medication: there was at least one measurable lesion according to RECIST 1.1 criteria, that is, the long diameter of non-lymph node lesion was >= 10 mm according to CT cross-sectional images or MRI, or the short diameter of lymph node lesion was >= 15 mm.

Exclusion criteria

Exclusion criteria: 1.Have received previous immunotherapy; 2.Other anti-tumor therapies (including chemotherapy, radiotherapy, and molecular targeted therapy) were received within 4 weeks prior to the start of treatment.

Design outcomes

Primary

MeasureTime frame
Objective response rate;Disease control rate;Progression-free survival;Toxic side effects;

Countries

China

Contacts

Public ContactRen Fang

the First Affiliated Hospital of Zhengzhou University

renfang@foxmail.com+86 13849115866

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026