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Effect of transversus abdominis plane block on MACBAR of sevoflurane during laparoscopic pneumoperitoneum stimulation

Effect of transversus abdominis plane block on MACBAR of sevoflurane during laparoscopic pneumoperitoneum stimulation

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100046517
Enrollment
Unknown
Registered
2021-05-18
Start date
2021-05-20
Completion date
Unknown
Last updated
2022-01-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gynecological laparoscopic surgery patients

Interventions

Sevoflurane + unilateral TAP group (Group T1):One side was given 0.33% ropivacaine 20ml, and the other side was given the same amount of normal saline for TAP
Sevoflurane + bilateral TAP group (Group T2):20 mL of 0.33% ropivacaine was given to both sides for TAP

Sponsors

Affiliated Hospital of North Sichuan Medical College
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1.ASA I-II grade; 2.Aged 18 to 65 years; 3.Seventy-five patients underwent elective gynecological laparoscopic surgery.

Exclusion criteria

Exclusion criteria: 1.Patients with history of cardiovascular disease; 2.Liver and kidney dysfunction; 3.A history of high blood pressure, diabetes, and stroke; 4.A history of alcoholism and drug abuse; 5.Preoperative alkali electrolyte imbalances, clotting disorders; 7.Recently taken on the cardiovascular system and the effect of adrenergic response drugs; 8.Pregnant patients; 9.Patients allergic to local anesthetics.

Design outcomes

Primary

MeasureTime frame
Minimal alveolar concentration of blocking adrengic response (MACBAR);

Secondary

MeasureTime frame
Heart rate (HR);Mean arterial blood pressure (MAP);Postoperative abdominal pain visual analogue scale score (VAS score);

Countries

China

Contacts

Public ContactJiang Pingping

Affiliated Hospital of North Sichuan Medical College

307174907@qq.com+86 15881496034

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 5, 2026