Pulmonary Hypertension
Conditions
Interventions
Control group:Placebo
Sponsors
The First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Aged 18 to 80 years, gender is not limited; 2.Meets the diagnostic standard of pulmonary hypertension; 3.Patients with fixed dose and type of conventional medicine last month; 4.Patients who did not receive targeted drug therapy or targeted drug therapy regimen fixed for at least a month; 5.Patients who had not received interventional or surgical treatment within 6 months before the trial; 6.Volunteer to participate in the clinical trial, understand and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1.Patients with acute exacerbation of chronic heart failure, acute myocardial infarction, coronary revascularization, and cardiac resynchronization within a month before the trial; 2.Patients with acute exacerbation of COPD/combined pulmonary infection within a month before the trial; 3.Patients with right ventricular outflow tract obstruction; 4.Patients with malignant tumors, mental disorders, malignant arrhythmias and other serious diseases; 5.Patients with severe renal disease (serum creatinine > 450umol/L) or liver disease (including serum transaminase >3 times the upper limit of normal value); 6.Patients who had taken Chinese medicine preparations (including TCM decoction pieces, granules, Proprietary Chinese medicine, TCM intravenous preparations, etc.) within 2 weeks before the trial; 7.Patients with disadvantageous activities of lower limbs and unable to cooperate with the completion of relevant examinations; 8.Pregnant women and lactating women; 9.Patients with known allergy to the drug ingredients and excipients in this trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pulmonary artery systolic pressure; | — |
Secondary
| Measure | Time frame |
|---|---|
| Six minutes walking distance;WHO functional class;Borg dyspnea scores;Ultrasonic cardiogram;Quality of Life Scale;Endothelin - 1;Nitric oxide; | — |
Countries
China
Contacts
Public ContactMao Jingyuan
The First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
Outcome results
None listed