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Clinical study on the effect of remazolam toluene sulfonate on cerebral blood flow perfusion

Clinical study on the effect of remazolam toluene sulfonate on cerebral blood flow perfusion

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100046501
Enrollment
Unknown
Registered
2021-05-17
Start date
2021-07-01
Completion date
Unknown
Last updated
2022-01-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cerebral blood perfusion

Interventions

The propofol group:Propofol injection sedation treatment
Rimazolam group:Remazolam toluene sulfonate was sedated for injection

Sponsors

Hengshui People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Patients receiving painless gastroenteroscopy, painless induced abortion and curettage in the outpatient department;Patients receiving invasive ventilation in ICU; 2.Aged > 18 years; 3.The hemodynamics was stable, and no vasoactive drugs were used; 4.During the experiment, all patients received BIS monitoring to evaluate the sedation depth in real time; 5.Can cooperate to complete the ultrasound examination.

Exclusion criteria

Exclusion criteria: 1.The skin of the neck is damaged or covered with sterile materials and cannot be scanned by ultrasound; 2.The presence of cervical vascular disease or anatomical structure changes; 3.Arrhythmias include atrial fibrillation, atrial premature beats, ventricular premature beats and atrioventricular block; 4.After temporary or permanent pacemaker implantation and prosthetic valve replacement; 5.The ultrasound image is not clear or the data is missing; 6.History of craniocerebral diseases.

Design outcomes

Primary

MeasureTime frame
Carotid artery contraction and diastolic velocity;Carotid resistance index;Carotid blood flow; Bispectral index value;

Secondary

MeasureTime frame
Heart rate;Blood pressure;

Countries

China

Contacts

Public ContactWang Jinlong

Hengshui People's Hospital

iamwjr306@163.com+86 18003188396

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026