Major Depression Disorder
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Meet ICD-10 criteria for MDD; 2.Baseline score of 17-item HAMD > 17; 3.Aged 12 to 18 years; 4.Right-handed; 5.Participants and their guardians sign the informed consent file.
Exclusion criteria
Exclusion criteria: 1.Exclude patients with other mental diseases other than current MDD; 2.Patients with depression caused by other systemic diseases and brain organic lesions were excluded; 3.Patients with a history of cranial diseases, imagination impairment, epileptic seizures, and other neurological diseases were excluded; 4.Patients with a history of serious systemic diseases such as cardiovascular system, respiratory system, and immune system were excluded; 5.Exclude patients with a history of alcohol and drug abuse; 6.Patients with metal implants such as dentures and pacemakers were excluded; 7.Women during pregnancy and lactation were excluded. 8.Patients receiving electroconvulsive therapy were excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| brain network connectivity;depression level; | — |
Countries
China
Contacts
Shenzhen University