Acute herps zoster
Conditions
Interventions
Sponsors
South District of Guang'anmen Hospital, China Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria for herpes zoster; 2. Aged range from 18 to 75 years; 3. No antiviral drugs or analgesics have been taken or used externally within 1 week; 4. Neuropathic pain vas value >= 50%; 5. Sign the informed consent form and volunteer to participate in this research.
Exclusion criteria
Exclusion criteria: 1. Special types, such as meningeal herpes zoster, visceral herpes zoster, eye and ear herpes zoster, generalized herpes zoster, non-rash type herpes zoster, etc.; 2. Patients who are highly allergic to amide local anesthetics or to any other ingredients in compound lidocaine cream; 3. Long-term use of corticosteroids or immunosuppressive agents; 4. Patients with congenital or idiopathic methemoglobinemia; 5. Women who are breastfeeding, pregnant or preparing to become pregnant; 6. Patients with severe primary diseases or systemic failure such as cardiovascular, cerebrovascular, liver, kidney, hematopoietic system, patients with atopic dermatitis, psychiatric patients, hemophilia patients, and patients with bleeding tendency; 7. Patients who are in a critical condition and are difficult to make an accurate assessment of the effectiveness and safety of the treatment; 8. Patients with scar constitution.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The change of the VAS score from baseline in the most painful degree of acute neuralgia in local herpes zoster; | — |
Secondary
| Measure | Time frame |
|---|---|
| The time required for constant pain intensity of VAS below 30%;Percentage of patients with the most painful VAS score of herpes zoster acute neuralgia decreased to less than 30%; | — |
Countries
China
Contacts
Public ContactGuo Yufeng
Guang'anmen Hospital, China Academy of Traditional Chinese Medicine
Outcome results
None listed