Postoperative cognitive dysfunction
Conditions
Interventions
Group 1:Routine fasting before surgery
Group 2:Oral 4ml/kg carbohydrate 2h before operation
Group 3:Oral 4ml/kg flavored distilled water 2h before operation
Sponsors
First Affiliated Hospital of Anhui Medical University
Eligibility
Sex/Gender
All
Age
65 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Elderly patients undergoing elective surgery, aged 65-80 years; 2. No gender limit; 3. American Society of Anesthesiologists (ASA) grade I-III; 4. Body mass index (BMI) 20-30 kg/m^2.
Exclusion criteria
Exclusion criteria: 1. Patients whose preoperative cognitive function is assessed as cognitive impairment (modified MMSE <26 or MMSE <24 and the patient's education level is below high school). 2. Emergency surgery patients. 3. Past history of gastrointestinal surgery, and patients with gastric emptying disorders (such as gastroesophageal reflux, history of chronic aspiration, delayed gastric emptying), gastrointestinal obstruction, and patients who cannot use enteral preparations. 4. Patients with high risk of severe cardiorenal insufficiency that affect the safety evaluation of the trial. 5. Patients with mental disorders, alcohol dependence, and drug abuse history. 6. Patients who have allergies or have been allergic to multiple drugs in the past, and those who are allergic to the relevant preparations needed in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Patient's cognitive function; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood sugar;Incidence of hypotension;Serum inflammatory factor content;Patient's subjective perception of VAS score;Adverse reaction rate;Overall patient satisfaction score; | — |
Countries
China
Contacts
Public ContactLiu Xuesheng
The First Affiliated Hospital of Anhui Medical University
Outcome results
None listed