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Sequential recruitment maneuvers during mechanical ventilation with high-flow nasal oxygen after extubation to prevent postoperative pulmonary complications in patients undergone thoracic surgery: a prospective randomized controlled trial

Sequential recruitment maneuvers during mechanical ventilation with high-flow nasal oxygen after extubation to prevent postoperative pulmonary complications in patients undergone thoracic surgery: a prospective randomized controlled trial

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100046356
Enrollment
Unknown
Registered
2021-05-14
Start date
2021-06-01
Completion date
Unknown
Last updated
2021-12-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative pulmonary complications after thoracic surgery

Interventions

experimental group 1:recruitment maneuver
experimental group 2:high-flow nasal oxygen

Sponsors

West China Hospital of Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18-80 years; 2. Patients undergoing elective pulmonary and mediastinal operations; 3. The patients who admitted to the ICU after surgery and received mechanical ventilation.

Exclusion criteria

Exclusion criteria: 1. Severe obesity (BMI >=35Kg/m2); 2. Shock caused by various reasons after operation; 3. Surgery has been performed within one month before the operation; 4. Pregnant women with mental illness or Parkinson's disease neuromuscular disease; 5. Invasive mechanical ventilation cannot be withdrawn within 24 hours after operation; 6. Tracheoesophageal fistula caused by surgery; 7. The patient and family members did not sign the informed consent.

Design outcomes

Primary

MeasureTime frame
The incidence of pulmonary complications;Level of pulmonary complications;

Secondary

MeasureTime frame
length of stay in the ICU;rate of mechanical ventilation after extubation;rate of reintubation;rate of readmission to the ICU;length of hospital stay; 28-day mortality rate ;

Countries

China

Contacts

Public ContactWang Bo

West China Hospital, Sichuan University

wchicu@126.com+86 13880768219

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 11, 2026