primary biliary cholangitis
Conditions
Interventions
Ursodeoxycholic acid group:Ursodeoxycholic acid
Rifaximin group :UDCA and rifaximin
Sponsors
Xiangya Hospital of Central South University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 75 years; 2. Patients with newly-onset primary biliary cholangitis; 3. Volunteer to participate in this study and sign a written informed consent.
Exclusion criteria
Exclusion criteria: 1. Have taken antibiotics in the past 2 months; 2. Take intestinal microecological preparations in the past 2 months; 3. Have a history of drinking in the past 3 months; 4. History of other liver diseases such as genetic metabolic diseases, hepatitis, liver cancer; 5. Infectious diarrhea, chronic diarrhea, irritable bowel syndrome, inflammatory diseases and other intestinal diseases; 6. Pregnant and lactating women; 7. Patients with serious mental illness, drug abuse, alcohol abuse, etc. who cannot cooperate with the study; 8. Those who have participated in any other clinical research within 1 month before entering the screening (Visit 1); 9. The investigator judges that any other diseases or conditions are not suitable for patients participating in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| liver function;Kidney function;Coagulation;Immunization full set;ANA Spectrum;Blood routine; | — |
Secondary
| Measure | Time frame |
|---|---|
| Anti-neutrophil antibody; | — |
Countries
China
Contacts
Public ContactLiu Xiaowei
Xiangya Hospital
Outcome results
None listed