Study on the mechanism of Mir-182 regulating histidine metabolism mediated T cell differentiation and immune paralysis in sepsis

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2100046327

Enrollment

Unknown

Registered

2021-05-14

Start date

2021-05-14

Completion date

Unknown

Last updated

2021-12-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

sepsis

Interventions

Gold Standard:sepsis3.0

Index test:Arginine, miR-182

Eligibility

Sex/Gender

All

Age

18 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1. In line with sepsis 3.0 standard issued jointly by SCCM and ESICM in 2016 to diagnose sepsis and septic shock patients; 2. Aged >= 18 years; 3. Sign informed consent.

Exclusion criteria

Exclusion criteria: 1. The patients who died within 48 hours or were discharged from the hospital with incomplete clinical data; 2. Patients who participated in other researchers at the same time.

Design outcomes

Primary

Measure	Time frame
Content and expression of microRNA-182;Content and expression of arginine;T cell ratio;	—

Countries

China

Contacts

Public ContactChen Longwang

The First Affiliated Hospital of Wenzhou Medical University

chenlongwang1129@126.com+86 15167735958

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026