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A clinical study on the use of S-ketamine in patients controlled intravenous analgesia (PCIA) after thoracoscopic lobectomy and perioperative depression and anxiety

A clinical study on the use of S-ketamine in patients controlled intravenous analgesia (PCIA) after thoracoscopic lobectomy and perioperative depression and anxiety

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100046317
Enrollment
Unknown
Registered
2021-05-13
Start date
2021-06-01
Completion date
Unknown
Last updated
2021-12-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative analgesia and anxiety and depression

Interventions

Sponsors

Affiliated Hospital of Guizhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1.Aged 18 to 65 years; 2.ASA I-II; 3.Male or female; 4.No preoperative diseases of vital organs, no cardiopulmonary, liver and kidney dysfunction, no history of chronic system, no history of cerebrovascular disease, no history of mental illness, no history of drug abuse, no recent use of analgesic drugs such as opioids and non-steroidal an-inflammatory drugs (NSAIDs); 5.Patients who did not participate in other clinical trials preoperatively; 6.Preoperative diagnosis and imaging examination of the patients with clear lung mass lesions, to be thoracoscopic lobectomy under general anesthesia.

Exclusion criteria

Exclusion criteria: 1.Patients with hyperthyroidism; 2.Cognitive dysfunction; 3.Allergy to the drug used in this study; 4.Intolerance to one-lung ventilation, history of rib fracture, history of iplateral lung surgery or trauma.

Design outcomes

Primary

MeasureTime frame
visual analogue scale;

Secondary

MeasureTime frame
Hospital Anxiety and Depression Scale;Ramsay sedation Scale;Press of PCA;Analgesic satisfaction;

Countries

China

Contacts

Public ContactZou Xiaohua

Affiliated Hospital of Guizhou Medical University

562931613@qq.com+86 13809416036

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026