colonoscopy
Conditions
Interventions
control group :sufentail 0.1µg/kg
experimental group 1:alfentanil 5µg/kg
experimental group 2:alfentanil 7.5µg/kg
experimental group 3:alfentanil 10µg/kg
Sponsors
The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.Aged 18 to 65 years, regardless of gender; 2.ASA I or II level; 3.Outpatients or inpatients undergoing elective painless colonoscopy or treatment; 4.The inspection time should be within 30 minutes (the inspection time is uniformly set as the time from the insertion of the colonoscope to the removal of the colonoscope); 5.Volunteer to participate and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1.People with chronic pain who have long-term use of analgesics, psychotropic drugs (including opioids, NSAIDs, sedatives, and antidepressants), alcohol abusers; 2.BMI > 30 kg/m2; 3.Abnormal liver and kidney function before surgery; 4.Preoperative hypertensive patients with systolic blood pressure > 180mmHg and/or diastolic blood pressure > 110mmHg, or patients with hypotension (blood pressure < 90/60mmHg); 5.Have a history of abnormal surgical anesthesia recovery; 6.Suffer from esophageal reflux disease; 7.Sedative or analgesic drugs were used 24 hours before the operation; 8.History of allergy to propofol, soy, glycerin or opioids; 9.Subjects with chronic lung disease; 10.Pregnant or parturient; 11.Suspected patients with difficult airways; 12.Participated in other drug trials within three months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| recovery time;discharge time; | — |
Secondary
| Measure | Time frame |
|---|---|
| directed force recovery time; | — |
Countries
China
Contacts
Public ContactWang Sheng
The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China
Outcome results
None listed