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Perioperative high-dose dexamethasone regimen does not increase infection rate in primary total joint arthroplasty: a retrospective large-scale study

Perioperative high-dose dexamethasone regimen does not increase infection rate in primary total joint arthroplasty: a retrospective large-scale study

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100046304
Enrollment
Unknown
Registered
2021-05-12
Start date
2021-05-12
Completion date
Unknown
Last updated
2021-12-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

End-stage arthropathy

Interventions

control group:no dexamethasone
low-dose group:dexamethasone = 15mg

Sponsors

West China Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to 94 Years

Inclusion criteria

Inclusion criteria: Primary total joint arthroplasty performed in West China Hospital for end-stage OA with or without intravenous usage of dexamethasone perioperatively.

Exclusion criteria

Exclusion criteria: 1.Total joint arthroplasty due to revision, inflammatory arthropathy, or sequela of joint infection; 2.Perioperative usage of other kinds of glucocorticoids; 3.Preoperative usage of glucocorticoids.

Design outcomes

Primary

MeasureTime frame
periprosthetic joint infection;—

Secondary

MeasureTime frame
wound compliactions;—

Countries

China

Contacts

Public ContactZhou Zongke

West China Hospital, Sichuan University

zhouzongke@scu.edu.cn+86 18980601028

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026