breast cancer
Conditions
Interventions
Control group:Placebo
Sponsors
Shanghai Baoshan Hospital of Integrated Traditional Chinese and Western Medicine
Eligibility
Sex/Gender
Female
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1. Patients signed informed consent and voluntarily joined the study; 2. Breast cancer was confirmed by pathology or Histocytology; 3. Excluding chemotherapy contraindications, breast cancer patients who plan to receive intravenous chemotherapy drugs; 4. At any time during the current chemotherapy regimen, although there were antiemetic drugs consistent with the guidelines, there was significant CINV. The specific criteria were: nausea and vomiting or the need for more than one supplementary antiemetic drug, and / or >= moderate nausea on the 5-level scale (0 = none, 1 = mild, 2 = moderate, 3 = severe, 4 = very severe); 5. The patient's ECoG status was 0, 1 or 2; 6. The researchers determined that the patient could be treated with Wuzhuyu decoction; 7. Aged >=18 years; 8. Life expectancy greater than or equal to 4 months; 9. Willing and able to comply with all research requirements, including treatment, time and nature of assessment required, including diary, quality of life, urine test and any statutory blood test.
Exclusion criteria
Exclusion criteria: 1. Allergic to traditional Chinese Medicine; 2. The researcher judged other conditions not suitable for inclusion in the study; 3. Symptomatic primary or secondary central nervous system malignancies; 4. Symptomatic gastrointestinal obstruction; 5. Disease related nausea or vomiting, need daily antiemetic treatment; 6. History of epilepsy or recurrent seizures; 7. Schizophrenia, other psychosis, severe personality disorder, except depression associated with underlying illness; 8. Patients who are pregnant, breast-feeding or lack of contraception. Women with fertility must have a negative pregnancy test 7 days before registration; 9. Patients who participated in other clinical trials in recent 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Vomit score; | — |
Countries
China
Contacts
Public ContactLi Tian
Shanghai Baoshan Hospital of Integrated Traditional Chinese and Western Medicine
Outcome results
None listed