Safety and efficacy of tranexamic acid in open reduction and internal fixation of calcaneal fractures: a prospective randomized controlled trial design

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100046281

Enrollment

Unknown

Registered

2021-05-12

Start date

2021-06-01

Completion date

Unknown

Last updated

2021-12-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Calcaneal fracture

Interventions

Experimental group:use tranexamic acid

Control group:blank

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Closed calcaneal fracture; 2. Tolerant with anesthesia and surgery; 3. Willing to cooperate with surgery and regular follow-up.

Exclusion criteria

Exclusion criteria: 1. Patients with rheumatoid arthritis, mandatory spondylitis, uncontrolled gout and other endocrine and rheumatic immune system diseases ; 2. Alcoholism and smoking ; 3. Uncontrolled diabetes, Especially in patients with diabetic peripheral neuropathy ; 4. Open calcaneal fractures ; 5. Systemic or local infection ; 6. Poor local soft tissue conditions after previous ankle surgery ; 7. Intolerance to surgery.

Design outcomes

Primary

Measure	Time frame
Hematological index;complications;Pain Score;Summary Form of health survey scores;	—

Countries

China

Contacts

Public ContactZhang Hui

West China hospital of Sichuan University

caesarzh@163.com+86 18980601437

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026