Exercising qi to eliminate fullness, open chest to eliminate paralysis. Used for coronary heart disease with turbid phlegm blocking the collaterals, stable angina pectoris.
Conditions
Interventions
Sponsors
First Affiliated Hospital of Zhengzhou University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 80 years; 2. Women of childbearing age must have a negative pregnancy test and are not breastfeeding, and must accept contraceptive methods approved by the researcher during the study; 3. Evidence of coronary artery disease, including a clear history of myocardial infarction (at least 3 months before enrollment), or significant coronary artery disease confirmed by non-invasive or invasive angiography; 4. Have symptoms that support the diagnosis of chronic angina pectoris and/or have a history of abnormal reactions to exercise (angina pectoris and/or cardiogram changes); 5. Patients with mild to moderate angina pectoris (CCS II or III); 6. The amount of chronic nitrate drugs used in the past (such as long-acting nitroglycerin), beta receptor blockers, calcium channel blockers, warfarin or other oral anticoagulant drugs can be gradually reduced or stopped By; 7. The patient must understand, be willing, able and comply with this research plan, and be able to understand the relevant contents of the diary card; 8. The patient must voluntarily sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients with ST-segment drop by more than 1mm before exercise in any lead, left bundle branch block, use of digoxin, left ventricular hypertrophy, WPW syndrome, and other patients who can interfere with the exercise plate electrocardiogram; 2. Arrhythmia of clinical significance, atrioventricular block above 1 degree; 3. Combined with other diseases of clinical significance, including severe liver and kidney insufficiency, pulmonary hypertension, chronic obstructive pulmonary disease, history of cerebral hemorrhage or epileptic seizures, medication is required; 4. History of congestive heart failure (heart function below grade 1 does not include grade 1), severe valvular disease, severe hypertension, severe anemia, suspected or known arterial dissection, acute myocarditis or pericarditis, thrombophlebitis, lung Embolism or history of myocardial infarction within 3 months; 5. Bleeding diathesis, or using warfarin; 6. Pacemaker implanters; 7. Can not stop taking chronic nitrate ester (such as long-acting nitroglycerin) treatment and only use short-acting nitroglycerin or a beta blocker or calcium channel blocker; 8. Participate in other clinical trials or take other research drugs within 90 days before screening; 9. Other situations that the researcher thinks are not suitable for participating in this research.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Angina pectoris symptoms curative effect;Electrocardiographic efficacy; | — |
Secondary
| Measure | Time frame |
|---|---|
| The weekly changes in the amount of nitroglycerin used for acute relief.; | — |
Countries
China
Contacts
Public ContactMeng Zhe
Outcome results
None listed