Hepatolenticular degeneration(Wilson's disease)
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Comply with WD diagnosis criteria of Western medicine; 2.Conformed to WD brain type; 3.Aged 15 to 35 years; 4.Patients with first diagnosis who had not received copper removal therapy with drugs such as dimercaptopropanesulfonate injection (DMPS) within 2 months before admission; 5.After careful specialist examination by two attending physicians or more, the patient's muscle tension was determined to be increased; 6.Informed consent was signed by the patient or his family.
Exclusion criteria
Exclusion criteria: 1. Patients who do not meet the clinical manifestations of phlegm and blood stasis intercombination; 2. Complicated with other diseases, proved to be unrelated to WD, and confirmed that there may be diseases affecting bone and muscle, such as craniocerebral trauma, infection, high fever, viral hepatitis, etc.; 3. Accompanied by mental disorders; 4. Severe insufficiency of heart, liver and kidney.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Muscle biomechanical properties;Spasticity rating scale;Wilson's disease; | — |
Secondary
| Measure | Time frame |
|---|---|
| activities of daily living; | — |
Countries
China
Contacts
The First Affiliated Hospital of Anhui University of Chinese Medicine