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Anesthetic effects of esketamine as an adjuvant of ropivacaine on brachial plexus block

Anesthetic effects of esketamine as an adjuvant of ropivacaine on brachial plexus block

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100046233
Enrollment
Unknown
Registered
2021-05-12
Start date
2021-05-11
Completion date
Unknown
Last updated
2021-12-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Upper arm injury

Interventions

Experimental group:0.5% ropivacaine hydrochloride injection + 0.1 mg/kg esketamine hydrochloride injection 30 ml
Control Group:0.5% ropivacaine hydrochloride injection 30 ml

Sponsors

The Second Department of the First Hospital of Jilin University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1.American Society of Anesthesiologists ASA grade I-II; 8.Heart, lung, liver and kidney functions are normal; 9.Aged 18 to 65 years; 10.A BMI of 18.5 to 27.9.

Exclusion criteria

Exclusion criteria: 1.The patient refused to undergo brachial plexus block anesthesia; 2.Patients with allergies to the active ingredient of ketamine or to all excipients; 3.Patients at serious risk of elevated blood pressure or intracranial pressure; 4.Patients with poorly controlled or untreated hypertension (arterial hypertension, resting systolic/diastolic blood pressure greater than 180/110mmHg); 5.Preeclampsia and eclampsia; 6.Patients with untreated or undertreated hyperthyroidism (hyperthyroidism); 7.Taking opioids for more than 10 days per day; 8.Puncture site infection or tumor; 9.Abnormal coagulation function; 10.Neuropsychiatric abnormalities; 11.History of diabetes; 12.History of allergy to narcotic drugs; 13.Cognitive impairment was observed by preoperative MMSE scale test. 14.Patients participating in other clinical studies.

Design outcomes

Primary

MeasureTime frame
Duration of analgesia;Time of loss of pain;

Secondary

MeasureTime frame
Duration of anesthesia operation;Length of operation;

Countries

China

Contacts

Public ContactQiu Jinpeng

The Second Department of the First Hospital of Jilin University

920378290@qq.com+86 13578895533

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026