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The clinical significance and application of corneal diseases in diabetic patients

The clinical significance and application of corneal diseases in diabetic patients

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100046206
Enrollment
Unknown
Registered
2021-05-10
Start date
2021-05-10
Completion date
Unknown
Last updated
2021-12-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 Diabetes Mellitus

Interventions

Diabetes without fundus disease group+diabetic non-proliferative retinopathy group+diabetic proliferative retinopathy group:N/A

Sponsors

The Union Hospital of Fujian Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. Meet the diabetes diagnostic criteria established by the American Diabetes Association (ADA) in 2019; 2. Regularly visit The Union Hospital of Fujian Medical University,and conduct standardized management at the National Standardized Metabolic Disease Management Center of our hospital; 3. Conscious, normal thinking,able to communicate in language; 4. Have a certain level of education, and have the ability to cooperate in completing the tests specified in the plan; 5. Volunteer to participate in this study and sign an informed consent form; 6. Did not participate in the clinical research of other drugs.

Exclusion criteria

Exclusion criteria: 1. There are other endocrine diseases; 2. Past history of eye trauma,keratitis and surgery; 3. Long-term wear history of contact lenses; 4. Combined with vascular dementia,Alzheimer's disease, Parkinson's,hepatolenticular degeneration, Huntington's disease and other diseases that clearly affect patients' cooperation in research; 5. Those who have a history of psychiatric diseases or family history,or are receiving anti-anxiety,anti-depressant and psychotropic medications; 6. Severe liver disease(such as liver cirrhosis,liver cancer,etc.),lung disease and extremely poor lung function(such as severe COPD,tuberculosis,interstitial lung disease,etc.),severe kidney disease(such as uremia,etc.); 7. Suffer from malignant tumor; 8. A history of alcoholism and alcohol dependence; 9. Severe illness,poor hearing,etc.unable to adhere to normal conversation and testing; 10. Women during pregnancy and lactation.

Design outcomes

Primary

MeasureTime frame
Confocal corneal detection;

Secondary

MeasureTime frame
The Michigan Diabetic Peripheral Neuropathy score;

Countries

China

Contacts

Public ContactLiu Libin

Department of Endocrinology and Metabolism, the Union Hospital of Fujian Medical University

libinliu@fjmu.edu.cn+86 591 86218562

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026