Diabetic foot
Conditions
Interventions
Group A:The umbilical cord mesenchymal stem cells were injected 20 ml
Group B:Routine wound care
Sponsors
Changhai Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 65 years; 2. Confirmed diagnosis of diabetic foot; 3. Diabetic foot ulcer lasted more than 2 weeks; 4. Wagner grade I or II, 1 cm2 = 20 mmHg; 5. Fertile women and non sterile men must agree to take effective contraceptive measures within 180 days after the administration of mesenchymal stem cells; 6. Subjects must understand and volunteer to give written informed consent.
Exclusion criteria
Exclusion criteria: 1. Overweight, body mass index (BMI) > 30; 2. Patients with uncontrolled diabetes were defined as HbA1c > 12%; 3. Ketoacidosis or hyperosmolar coma patients; 4. To study the patients who underwent recent surgery; 5. Patients with severe dysfunction of heart, liver, lung, kidney and other important organs; 6. Patients with severe coagulation dysfunction; 7. Severe, uncontrollable infection or even sepsis (in accordance with the mild infection standard of diabetic foot of American infectious disease association IDSA and international diabetic foot working group IWGDF, except those that are considered not to affect the study by the researchers); 8. Pregnant and lactating patients; 9. Patients with history of tumor; 10. Severe allergic history; 11. The patient has any potential mental illness of current medical certification; 12. All kinds of acute hepatitis, hepatitis B carriers, syphilis, HIV antibody positive, clear / suspected tuberculosis diagnosis; 13. Patients who ever participated in another clinical trials in recent 3 months; 14. With any other condition which judge by the investigator to unsuitation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Wound healing rate; | — |
Countries
China
Contacts
Public ContactZhu Feng
Changhai Hospital
Outcome results
None listed