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A clinical study on the use of ketamine in patients controlled intravenous analgesia (PCIA) after thoracoscopic lobectomy and perioperative depression and anxiety

A clinical study on the use of ketamine in patients controlled intravenous analgesia (PCIA) after thoracoscopic lobectomy and perioperative depression and anxiety

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100046166
Enrollment
Unknown
Registered
2021-05-07
Start date
2021-06-01
Completion date
Unknown
Last updated
2021-12-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative analgesia and anxiety and depression

Interventions

Sponsors

Affiliated Hospital of Guizhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Aged between 18 and 65 years old; 2. ASA ?-II, male or female; 3. No preoperative diseases of vital organs, no history of mental illness; 4. No history of drug abuse, no recent use of analgesic drugs such as opioids and non-steroidal-inflammatory drugs. 5. Patients who did not participate in other clinical trials preoperatively. 6. Preoperative diagnosis and imaging examination of the patients with clear lung mass lesions, to be thoracoscopic lobectomy under general anesthesia.

Exclusion criteria

Exclusion criteria: 1. Patients with hyperthyroidism, unwell controlled hypertension; 2. Patients with cognitive dysfunction, allergy to the drug used in this study; 3. Patients with intolerance to one-lung ventilation, history of rib fracture, history of lateral lung surgery, or trauma.

Design outcomes

Primary

MeasureTime frame
Visual analogue scale;

Secondary

MeasureTime frame
Hospital Anxiety and Depression Scale;Ramsay sedation Scale;Press of PCA;Analgesic satisfaction;

Countries

China

Contacts

Public ContactZou Xiaohua

Affiliated Hospital of Guizhou Medical University

562931613@qq.com+86 13809416036

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026