neovascular age-related macular degeneration
Conditions
Interventions
T&E Group:Nil
PRN group:Nil
Sponsors
The Second Affiliated Hospital of Harbin Medical University
Eligibility
Sex/Gender
All
Age
50 Years to 95 Years
Inclusion criteria
Inclusion criteria: 1. Patients diagnosed as monocular or binocular nAMD, BCVA is 0.05-0.5 (23-73 letters); 2. Before the COVID-19 epidemic, the patient received intravitreal injection of arbacicept treatment with 3+T&E, or 3+PRN therapeutic regime; 3. During the epidemic period, there was no follow-up and no treatment; 4. After the end of the epidemic, continue to treat and follow-up in our hospital; 5. The last follow-up showed that the disease was stable as follows: (1) The best corrected visual acuity lost no more than 5 letters (or one line) compared with the previous follow-up; (2) The CRT increased by no more than 10% compared with the previous follow-up; (3) OCT showed no obvious increase of effusion compared with the previous follow-up; (4) OCT showed no obvious new effusion; (5) No obvious new haemorrhage; (6) No new CNV on octa.
Exclusion criteria
Exclusion criteria: 1.New CNV or CME caused by other reasons; 2.Patients has been treated with laser, PDT and other treatments in the past; 3.Patients who had received anti-VEGF treatment in the study eye or contralateral eye in the past 3 months; 4.Patients with neovascularization of anterior segment (including iris and angle) or neovascular glaucoma; 5.The study eyes had undergone vitreoretinal surgery and / or scleral buckling; 6.Patients who were not treated and followed up according to the specified treatment plan.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Central retinal thickness; | — |
Secondary
| Measure | Time frame |
|---|---|
| Best corrected visual acuity;subretinal fluid;intraretinal fluid;subretinal hyperreflective material;choroidal neovascularization;subretinal choroidal thickness; | — |
Countries
China
Contacts
Public ContactSun Dawei
Department of Ophthalmology, Second Affiliated Hospital of Harbin Medical University
Outcome results
None listed