Adverse events caused by opioid
Conditions
Interventions
Control group:Traditional anesthesia method
Experiment group:Dexmedetomidine, Lidocaine
Sponsors
The Second Xiangya Hospital of Central South University
Eligibility
Sex/Gender
All
Age
16 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Aged >= 16 years, no gender limit, BMI 18.9-30kg/m2, ASA classification I-II; 2. Patients who underwent elective sinusitis and endoscopic sinus surgery under general anesthesia for tracheal intubation, and the operation time >= 30 minutes; 3. In line with ethics, the patient voluntarily takes the test and signs the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients suffering from mental or nervous system diseases or suspected dementia or memory impairment; 2. Patients with severe impairment of auditory, visual, and language systems; 3. Patients with severe liver and kidney disease (Child-Pugh grade C or preoperative dialysis patients); 4. Patients who have been judged to have cognitive dysfunction before surgery; 5. Determined/suspected to abuse or use narcotic sedatives and analgesics for a long time 6. Patients who have contraindications or allergies to narcotic drugs; 7. Patients who do not cooperate or cannot understand QoR-40, NRS/VAS scores.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quality of Recovery-40 score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative wake-up time;Extubation time;VAS score;Adverse reactions after surgery; | — |
Countries
China
Contacts
Public ContactCao Lijun
The Second Xiangya Hospital of Central South University
Outcome results
None listed