H. pylori infection
Conditions
Interventions
experimental group:probiotics combined to Hp eradication therapy
control group:Hp eradication therapy
Sponsors
Sichuan Academy of Medical Sciences/Sichuan Provincial People's Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Adult patients, aged from 18 to 70 years; 2.Confirmation of Hp infection: (1)13C/14C urea breath test was positive; (2)Gastric mucosa Hp immunohistochemistry was positive; (3)Hp culture was positive, and the above two were consistent.
Exclusion criteria
Exclusion criteria: 1.Antibiotics and bismuth agents were taken within 4 weeks before this treatment or patients had taken PPI, H2 receptor antagonist or p-CAB within 2 weeks before treatment; 2.Pregnant or lactating women; 3. People who are allergic to or contraindicated with the experimental drugs used in this study; 4.Participated in other drug trials within 3 months prior to treatment in this trial; 5.If there are other serious diseases that affect the evaluation of this study or cannot express their chief complaint correctly, they cannot cooperate; 6.Subjects with dysphagia; 7. Patients with malignant tumors, serious comorbiditions, severe ulcer bleeding or perforation; 8.Patients judged by the investigator to be unsuitable for the clinical trial; 9.Those who are unwilling to sign the informed consent for the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Eradication rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Patient compliance;Incidence of adverse reactions; | — |
Countries
China
Contacts
Public ContactHan Shengxi
Sichuan Academy of Medical Sciences/Sichuan Provincial People's Hospital
Outcome results
None listed