Melasma
Conditions
Sponsors
Dongzhimen Hospital, Beijing University of Chinese Medicine
Eligibility
Sex/Gender
Female
Age
27 Years to 55 Years
Inclusion criteria
Inclusion criteria: 1. Female patients aged 27 to 55 years; 2. Diagnosis of melasma according to the Diagnostic and Treatment Criteria of Melasma and Leukoderma of the Chinese Society of Integrated Traditional Chinese and Western Medicine; 3. Symptoms have been present for more than 1 month; 4. Patients with moderate to severe melasma, moderate is defined with a modified Melasma Area and Severity Index (mMASI) score of 5.8 to 7.9,and severe melasma is those with a mMASI > 8; 5. Patients who have not been treated for other melasma treatment in the past three months; 6. Avoid ultraviolet rays and oral contraceptives during treatment; 7. Sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Pregnant or nursing women; 2. Diseases such as cardiovascular, cerebrovascular, liver, kidney, blood system and mental disorders; 3. Patients with other facial pigmentation diseases, such as: zygomatic brown mole, melanosis, and pigmented actinic lichen planus, etc; 4. Coagulation disorders (such as hemophilia, etc.); 5. Have a history of allergy to catgut; 6. Participation in another clinical study in the past 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Melasma Area and Severity Index(MASI); | — |
Secondary
| Measure | Time frame |
|---|---|
| The Dermatology Life Quality Index (DLQL);Melasma Area and Severity Index, MASI;Investigator's Global Assessment, IGA;The number of adverse reactions; | — |
Countries
China
Contacts
Public ContactWang Guangan
The Third Affiliated Hospital of Henan University of Traditional Chinese Medicine
Outcome results
None listed