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A single-center clinical study on the protective effect of lysozyme eye drops on ocular surface of patients wearing orthokeratology lens

A single-center clinical study on the protective effect of lysozyme eye drops on ocular surface of patients wearing orthokeratology lens

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100046119
Enrollment
Unknown
Registered
2021-05-04
Start date
2021-05-01
Completion date
Unknown
Last updated
2021-12-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

myopia, orthokeratology lens, inflammatory reaction of conjunctiva

Interventions

treatmeat group:use lysozyme eye drops
control group:use sodium hyaluronate eye drops

Sponsors

Beijing Remote Vision Ophthalmology Outpatient Department Co., Ltd. Optometry Outpatient Department
Lead Sponsor

Eligibility

Sex/Gender
All
Age
8 Years to 14 Years

Inclusion criteria

Inclusion criteria: 1.Aged 8 to 14 years; 2.Patients requiring orthokeratology lenses have no previous history of contact lens wear; 3.The conjunctiva of the blepharoplasty was normal, but the angular conjunctiva was not abnormal; 4.Diopter: sphericity=10 seconds, Shirmer test>=10mm/min; 5.Be willing to participate in this clinic test and can cooperate to complete the whole test.

Exclusion criteria

Exclusion criteria: 1.Eyelid eversion, ectropion, trichiasis, corneal ulcers, trachoma, keratitis, blepharitis/blepharoadenitis, blepharoadenitis/blepharoadenocyst, eye injuries, lesions caused by corneal foreign bodies, burns, dacryocystitis and other infections, etc.; 3.Allergic to this product; 4.Patients with serious primary diseases and mental disorders such as liver, kidney and hematopoietic system.

Design outcomes

Primary

MeasureTime frame
Bacterial detection rate;Ocular surface disease index score;Corneal and conjunctival grading;adverse reaction records;

Countries

China

Contacts

Public ContactXie Peiying

Beijing Remote Vision Ophthalmology Outpatient Department Co., LTD. Optometry Outpatient Department

x60@vip.163.com+86 13910849119

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026