Skip to content

Effects of anxiety on adverse reactions after general anesthesia in breast cancer patients

Effects of anxiety on adverse reactions after general anesthesia in breast cancer patients

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100046115
Enrollment
Unknown
Registered
2021-05-04
Start date
2021-05-20
Completion date
Unknown
Last updated
2021-12-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breast cancer

Interventions

Low anxiety group:Psychological comfort
High anxiety group:Psychological comfort
High anxiety intervention group:Psychotherapy and oral administration of estazolam before surgery

Sponsors

Department of Anesthesiology, the Second Affiliated Hospital of Harbin Medical University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1.Breast cancer patients undergoing surgery; 2.ASA classification I~II; 3.Aged 18~60 years; 4.The weight of 50~75kg; 5.Patients with education level not lower than primary school.

Exclusion criteria

Exclusion criteria: 1.History of mental illness, abnormal cognitive function, and history of psychotropic drug use; 2.Severe diseases of the central nervous system; 3.Serious cardiovascular disease, kidney disease, diabetes, liver disease; 4.A long history of heavy drinking and smoking; 5.Patients with chronic pain and long-term use of sedative and analgesic drugs.

Design outcomes

Primary

MeasureTime frame
Anxiety score;Incidence of postoperative nausea and vomiting;

Secondary

MeasureTime frame
Postoperative pain score;Heart rate variability;

Countries

China

Contacts

Public ContactLiu Jing

The Second Affiliated Hospital of Harbin Medical University

liujinghmu@126.com+86 15045621596

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026