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Determining optimal clinical target volume margins in high-grade glioma based on microscopic tumor extension and magnetic resonance imaging

Determining optimal clinical target volume margins in high-grade glioma based on microscopic tumor extension and magnetic resonance imaging

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100046106
Enrollment
Unknown
Registered
2021-05-04
Start date
2017-06-01
Completion date
Unknown
Last updated
2021-12-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Glioma

Interventions

Gold Standard:Diagnostic report of pathology department of Shandong Cancer Hospital
Magnetic&#32
Resonance&#32
with&#32
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Sponsors

Shandong Cancer Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Aged >= 18 years; 2. Preoperative Karnofsky Performance Status (KPS)>= 80; 3. Unifocal enhancing tumor on T1-weighted MRI; 4. Tumor located in nonfunctional area and successful supratotal resection; 5. Tumor removal achieved with resection margins that included the neighboring normal tissue (between 2cm and 3cm away from the tumor border).

Exclusion criteria

Exclusion criteria: 1. A medical history of brain chemoradiotherapy; 2. Multicentric or multifocal cerebral lesions.

Design outcomes

Primary

MeasureTime frame
ME, AUC of ROC;

Secondary

MeasureTime frame
MGMT, IDH, 1p/19q;

Countries

China

Contacts

Public ContactHu Man

Shandong Cancer Hospital

human5770@163.com+86 15762961001

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 22, 2026