Chronic obstructive pulmonary disease
Conditions
Interventions
Acute exacerbation group:Give patients standard treatment of acute exacerbation by the senior attending physician according to GOLD guideline.
Stable group:Give patients standard treatment of stable stage by the senior attending physician according to GOLD guideline.
Sponsors
Geriatric Hospital of Nanjing Medical University
Eligibility
Sex/Gender
All
Age
60 Years to 85 Years
Inclusion criteria
Inclusion criteria: AECOPD patients admitted for treatment and signed informed consent (refer to GOLD 2020 standards, COPD is defined as: dyspnea, chronic cough or sputum expectoration, history of exposure to risk factors, FEV1/FVC<0.70 after inhalation of bronchodilators; AECOPD is defined as COPD patients with worsening acute respiratory symptoms and requiring additional treatment).
Exclusion criteria
Exclusion criteria: 1. Patients with severe illness or other comorbidities that may affect the results of the study; 2. Patients requiring invasive mechanical ventilation; combined with neuromuscular disease, asthma-COPD overlap syndrome, OSA-COPD overlap syndrome, severe cardiovascular disease, pulmonary embolism, severe pneumonia, lung cancer, severe interstitial pneumonia , Patients with severe liver and kidney dysfunction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diaphragm electromyogram;Polysomnography;BNP, Leptin, Resistin and IL et al;Stop-Bang;Epworth Sleepiness Score;Epworth Sleepiness Score; | — |
Countries
China
Contacts
Public ContactLiu Jiannan, Lu gan
Department of Respiratory Medicine, Geriatric Hospital of Nanjing Medical University
Outcome results
None listed