postoperative analgesia
Conditions
Interventions
experimental group:Gabapentin combined with sufentanil
control group:Placebo
Sponsors
Beijing Tiantan Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Select intraspinal tumor resection patients who complained of pain before neurosurgery and included them in the study; 2. American Association of Anesthesiologists (ASA) grade I to II, aged 18 to 65 years.
Exclusion criteria
Exclusion criteria: 1. People with a history of drug abuse, mental illness and obesity; 2. Are taking carbamazepine or gabapentin or pregabalin; 3. Communication barriers; 4. Propofol, opioids and gabapentin contraindications (such as allergies); 5. Unable to use patient-controlled analgesia device (PCA pump) or unable to understand how to use the device.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| consumption of sufentanil; | — |
Secondary
| Measure | Time frame |
|---|---|
| Von Frey mechanical pain threshold, tenderness threshold;Neuropathic pain score;Visual analogue pain score;side effects: nausea, vomiting, drowsiness;Postoperative rehabilitation indicators: the duration of postoperative gastrointestinal function recovery, first feeding time, first time to go to the ground, discharge time, medical expenses; | — |
Countries
China
Contacts
Public ContactYue Hongli
Beijing Tiantan Hospital, Capital Medical University
Outcome results
None listed