Application of Pathogen Metagenomics Technology (mNGS) in Early Pathogen Identification and Host Immune Response of Sepsis

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2100046053

Enrollment

Unknown

Registered

2021-05-03

Start date

2021-04-30

Completion date

Unknown

Last updated

2021-12-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

sepsis

Interventions

Gold Standard:blood culture

Index test:Metagenomic&#32

sequencing

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18 to 80 years; 2. Meet the definition and diagnostic criteria of Sepsis 3.0; 3. Sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. During breastfeeding or pregnancy; 2. Decrease of neutrophils; 3. Those who have used long-term immunosuppressive agents in the past month (using hormones for more than 7 days).

Design outcomes

Primary

Measure	Time frame
Metagenomic sequencing;SEN, SPE, ACC, AUC of ROC;	—

Countries

China

Contacts

Public ContactQin Bingyu

Henan Provincial People's Hospital

qinbyu@126.com+86 13633810677

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026