Tuberculosis empyema
Conditions
Interventions
Group 1:Fixed PEEP
Group 2:Titrating PEEP according to driving pressure
Sponsors
Shenzhen Third People’s Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-65 years; 2. 18<BMI<24 3. One-lung ventilation during the operation; 4. American Association of Anesthesiology Score (ASA) grade I-III; 5. Patients who are willing to sign the informed consent and are willing to be followed up.
Exclusion criteria
Exclusion criteria: 1. Preoperative chest CT showed the presence of pleural effusion or atelectasis in the non-operative lung lobes; 2. Patients have contraindications for PEEP, such as high intracranial pressure, bronchopleural fistula, hypovolemic shock, right heart failure; 3. The patient refuses to participate in the trial or the patient withdraws from the trial halfway; 4. Bleeding volume>500ml or severe hypotension (mean arterial pressure <55 mmHg under the use of vasoactive drugs).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| lung ultrasound score;postoperative pulmonary complications; | — |
Secondary
| Measure | Time frame |
|---|---|
| oxygenation index;intrapulmonary shunt;lung compliance; | — |
Countries
China
Contacts
Public ContactYe Fangfan
Shenzhen Third People’s Hospital
Outcome results
None listed