Neural mechanisms of a new transcranial magnetic stimulation treatment protocol on major depression patients

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100046042

Enrollment

Unknown

Registered

2021-05-02

Start date

2021-04-30

Completion date

Unknown

Last updated

2024-10-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

major depression disorder

Interventions

Experimental group:Repetitive transcranial magnetic stimulation

Control group:False stimulus

Eligibility

Sex/Gender

All

Age

18 Years to 55 Years

Inclusion criteria

Inclusion criteria: 1. Major depression, obsessive-compulsive disorder and substance abuse diagnosed by DSM-V; 2. The Montgomery Depression Scale score is greater than or equal to 20; 3. Aged 18 to 55 years; 4. Agree to sign the consent form; 5. At least one drug fails under the appropriate dose and duration; 6. Take stable medication at least 4 weeks before transcranial magnetic stimulation treatment.

Exclusion criteria

Exclusion criteria: 1. Psychotic symptoms, schizophrenia, obsessive-compulsive disorder, severe addiction, bipolar disorder, suicidal behavior; 2. History of epilepsy, stroke, epilepsy or closed head injury or other major medical or neurological diseases; 3. History of brain trauma; 4. The history of ECT / MECT / TMS; 5. Fixed metal implanted in the body; 6. Claustrophobia; 7. Be pregnant.

Design outcomes

Primary

Measure	Time frame
Montgomery depression scale score;	—

Secondary

Measure	Time frame
Cognitive tasks;Patient health questionnaire;Baker depression scale;	—

Countries

China

Contacts

Public ContactLiu Wenjuan

Zhongshan Hospital, Fudan University

liu.wenjuan@zs-hospital.sh.cn+86 17621683506

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026