COVID-19
Conditions
Interventions
Patients previously infected with SARS-Cov2 group:COVID-19 vaccination
Normal healthy subjects:COVID-19 vaccination
Sponsors
West China Hospital of Sichuan University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Aged 18 to 60 years; 2.Patients previously infected with SARS-Cov2 (who have recovered for more than 6 months); 3.Normal healthy subjects; 4.Able to understand and voluntarily sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Women who are pregnant or breastfeeding, have a pregnancy plan within six months; 2. Those who are allergic to any component in the vaccine, or have allergies during previous vaccination of similar vaccines; 3. People who have experienced severe allergic reactions to vaccines in the past (such as acute allergic reactions, angioedema, dyspnea, etc.); 4. Have received immunosuppressant therapy, cytotoxic therapy, and inhaled corticosteroids in the past 6 months (excluding corticosteroid spray therapy for allergic rhinitis, and surface corticosteroid therapy for acute non-complicated dermatitis); 5. Receive blood products within 3 months before receiving the test vaccine; 6. Received live attenuated vaccine within 14 days before vaccination or subunit or inactivated vaccine within 7 days; 7. According to the judgment of the investigator, the subject has any other factors that are not suitable for participating in the clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| SARS - Cov2 specificity antibody;neutralizing antibody;specific T cells;memorable B cells; | — |
Countries
China
Contacts
Public ContactLi Yalun
West China Hospital, Sichuan University
Outcome results
None listed