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The Intervention of Chinese Medicine on NETs Formation of Pneumonia Sepsis

The Trial of the Intervention on Pneumonia Sepsis by Regulating the Formation of Circulating Neutrophil Extracellular Traps Basing on Rule of Removing Stasis, Detoxifying and Tonifying Qi

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100045954
Enrollment
Unknown
Registered
2021-04-30
Start date
2021-05-05
Completion date
Unknown
Last updated
2021-12-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pneumonia sepsis

Interventions

Sponsors

Longhua Hospital Shanghai University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. Meeting the diagnostic criteria of Sepsis3.0 and pulmonary infection; 2. Meeting the Chinese medicine criteria of stasis and toxin; 3. Aged 18-90 years; 4. Signing the informed consent file.

Exclusion criteria

Exclusion criteria: 1. The lung tumor or pulmonary tuberculosis induced pulmonary infection; 2. The severe inhibition of immune system, for example, AIDS, chemoradiotherapy of tumor or rheumatic connective tissue disease; 3. Dying after admission within 24 hours; 4. Having allergic history of the medicine; 5. Gestation, preparing a pregnancy or suckling period; 6. Patients with mental disorder; 7. Unable to take Chinese medicine for any reasons; 8. Fasting for any reasons.

Design outcomes

Primary

MeasureTime frame
circulating white blood count;APACHE II score;C-reaction protein;procalcitonin;

Secondary

MeasureTime frame
plasma NE-DNA;vital signs;traditional Chinese medicine syndrome estimate;inflammation score;coagulation function;oxygenation index;mechanical ventilation;chest X-ray;in-hospital mortality;

Countries

China

Contacts

Public ContactYao Miao'en

Longhua Hospital Shanghai University of Traditional Chinese Medicine

806585449@qq.com+86 19821267183

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026