Cerebral Hemorrhage
Conditions
Interventions
Group A:internal medicine
Group B:MRI navigation+minimally invasive surgery
Group C:neuroendoscopy+minimally invasive surgery
Group D:AR+AI+minimally invasive surgery
Sponsors
Huashan Hospital, Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 80 years; 2. GCS = 6; 3. Spontaneous supratentorial hemorrhage >= 30ml; 4. Within 12 hours after symptoms onset; 5. Willing to receive minimally invasive surgery within 48 hours after ICH; 6. Hematoma volume increase<=5 ml after 6 hours; 7. Systolic pressure < 200 mmHg and lasted for at least 6 hours; 8. Modified Rankin Scale scored 0 or 1 before ICH; 9. Signed an informed consent form.
Exclusion criteria
Exclusion criteria: 1. ICH in brainstem; 2. platelet 1.4; 3. Patients with coagulopathy; 4. Accompanied by serious diseases, including liver disease, kidney disease, digestive system, cardiovascular system, respiratory system, endocrine system, blood system, immune system, etc.; 5. Mechanical valve implantation; 6. Unstable intracranial space occupying or progressive intracranial hypertension syndrome; 7. Irreversible brain stem failure (fixation of eyeball, dilation of pupil, decancephalization, etc.) or Glasgow coma scale <= 4; 8. Included in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sequential analysis of Modified-Rankin-Scale scores; | — |
Secondary
| Measure | Time frame |
|---|---|
| Death or disability (Modified Rankin Scale scored 3-6); | — |
Countries
China
Contacts
Public ContactYang Liusong, Tang Yuping
Huashan Hospital, Fudan University
Outcome results
None listed