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A Comparative Study on the Safety and Efficacy of Esmketamine Versus Dexmedetomidine During Drug Induced Sleep Endoscopy in Children With Positional Obstructive Sleep Apnea: A Consort-Prospective, Randomized, Controlled Clinical Trial

A Comparative Study on the Safety and Efficacy of Esmketamine Versus Dexmedetomidine During Drug Induced Sleep Endoscopy in Children With Positional Obstructive Sleep Apnea: A Consort-Prospective, Randomized, Controlled Clinical Trial

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100045914
Enrollment
Unknown
Registered
2021-04-28
Start date
2021-06-01
Completion date
Unknown
Last updated
2021-12-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obstructive Sleep Apnea Syndrome

Interventions

Group D:IV Dexmedetomidine
Group K:IV esketamine

Sponsors

Zhongnan Hospital of Wuhan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
3 Years to 12 Years

Inclusion criteria

Inclusion criteria: 1. Presenting for an elective tonsillectomy /adenoidectomy during general anesthesia; 2. ASA I-II; 3. Aged 3 to 12 years; 4. No chronic heart/lung/liver/kidney diseases, psychiatric illness.

Exclusion criteria

Exclusion criteria: 1. Allergy against the study medications (DEX or esketamine); 2. Individual or family history of malignant hyperthermia; 3. Presence of a tracheostomy or other artificial airway adjunct.

Design outcomes

Primary

MeasureTime frame
Heart rate;Pulse oxygen saturation;Drug dosages;Score;Onset time;—

Countries

China

Contacts

Public ContactSong Xuemin

Zhongnan Hospital of Wuhan University

sxmcl1018@163.com+86 18986073715

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 12, 2026