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Research on Immediate Electrophysiological and Biomechanical Effects and Therapeutic Mechanism of Lower Limb Positive Pressure Treadmill Training for Improving Pathological Gait after Stroke

Research on Immediate Electrophysiological and Biomechanical Effects and Therapeutic Mechanism of Lower Limb Positive Pressure Treadmill Training for Improving Pathological Gait after Stroke

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100045912
Enrollment
Unknown
Registered
2021-04-28
Start date
2021-04-27
Completion date
Unknown
Last updated
2021-12-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke

Interventions

stroke group:LBPP treadmill training
HCs group:none

Sponsors

The Fifth Affiliated Hospital of Guangzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Stroke Group (1) According to the national stroke diagnostic criteria established by the 4th Cerebrovascular Diseases Conference; (2) Confirmed by CT or MRI as stroke; (3) Lower limb dysfunction caused by stroke, and have a capacity to walk or stand with /without stick; (4) Brunnstrom score from 3 to 5; (5) MMSE >= 10; (6) 4 >= FAC >= 2; (7) Voluntarily signing up informed consent. 2. Heathy elderly Group (HEs Group) (1) The age is 60-75 years old; (2) The limbs are healthy and able to walk independently; (3) MMSE 24 points or higher; (4) Voluntarily signed the informed consent. 3. Heathy control Group (HCs Group) (1) The age is 18-28 years old; (2) The limbs are healthy and able to walk independently; (3) MMSE 24 points or higher; (4) Voluntarily signed the informed consent.

Exclusion criteria

Exclusion criteria: 1. Stroke Group (1) Previous diseases affecting walking ability, such as lower limb fracture history, lower limb symptoms after lumbar disc herniation, lower limb pain, etc.; (2) unstable condition or changes in the condition during the experiment, which affect the experimental results; (3) Patients with severe heart, lung, liver, and kidney diseases who could not complete the experiment; (4) Unable to cooperate with the completion of the experiment, there are serious cognitive dysfunction or aphasia;5 suffer from serious mental disorders. 2. HEs Group (1) Previous diseases affecting walking ability, such as lower limb fracture history, lower limb symptoms after lumbar disc herniation, lower limb pain, etc.; (2) Patients with severe heart, lung, liver and kidney diseases who could not complete the experiment; (3) Unable to cooperate with the completion of the experiment, there are serious cognitive dysfunction or aphasia; (4) Suffer from serious mental disorders. 3. HCs Group (1) Previous diseases affecting walking ability, such as lower limb fracture history, lower limb symptoms after lumbar disc herniation, lower limb pain, etc.; (2) Unable to cooperate with the completion of the experiment, there are serious cognitive dysfunction or aphasia; (3) Suffer from serious mental disorders.

Design outcomes

Primary

MeasureTime frame
Electromyography;

Secondary

MeasureTime frame
10-meter walk test, 10 MWT;Time up and go, TUG;Activities of daily living;Berg Balance Scale, BBS;

Countries

China

Contacts

Public ContactLiang Junjie

The Fifth Affiliated Hospital of Guangzhou Medical University

ljj88961@gzhmu.edu.cn+86 13828405123

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026