High-risk HPV persistent infection
Conditions
Interventions
Sponsors
Anhui Province Maternity and Child Healthcare Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Women aged 18 to 70 years with sexual life, but non-pregnant or lactating; 2. Persistent hr-HPV infection for more than twelve months; 3. For each individual patient, only either HPV genotyping test or HPV E6/E7 mRNA assay was used for the examination of hrHPV infection during whole observation from the screening of enrollment to the end of follow-up; 4. Without a high level of cervical lesions [no more than grade one cervical intraepithelial neoplasia (CIN I) according to the examination of colposcopy and biopsy]; 5. No previous anti-HPV intervention.
Exclusion criteria
Exclusion criteria: 1. With a history of allergy, smoking, oral contraceptive, and HPV vaccination; 2. With severe heart, lung, liver, and kidney dysfunction; 3. Women who can't complete the designed drug administration due to menstrual disorder.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HPV E6E7 mRNA;HPV-DNA genotyping test; | — |
Countries
China
Contacts
Public ContactZhou Shuguang
Anhui Province Maternity and Child Healthcare Hospital
Outcome results
None listed