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Based on lung protective ventilation strategies: the effect of driving pressure-guided individualized PEEP setting on early pulmonary function of patients with laparoscopic colorectal surgery

Based on lung protective ventilation strategies: the effect of driving pressure-guided individualized PEEP setting on early pulmonary function of patients with laparoscopic colorectal surgery

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100045903
Enrollment
Unknown
Registered
2021-04-27
Start date
2021-04-30
Completion date
Unknown
Last updated
2021-12-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

laparoscopic colorectal surgery

Interventions

control group:Traditional Lung Protective Ventilation Strategy, PEEP=5 cmH2O
experimental group:Driving pressure-guided individualized PEEP

Sponsors

West China Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Aged >= 18 years; 2. Will undergo laparoscopic colorectal surgery; 3. Operation time >= 2 hours; 4. ASA classification II-III; 5. Written inform consent.

Exclusion criteria

Exclusion criteria: 1.Cannot cooperate for any reason or not suitable for investigator; 2.Re-laparoscopic surgery during hospitalization; 3.Patient who has done preoperative mechanical ventilation; 4.Acute lung injury or acute respiratory distress syndrome history within 3 months before operation; 5.Severe hepatic and kidney insufficiency; 6.Women during pregnancy and lactation; 7.Other clinical trials participation.

Design outcomes

Primary

MeasureTime frame
Oxygenation index, OI;—

Countries

China

Contacts

Public ContactHai Yu

West China School of Medicine, Sichuan University

yuhaishan117@yahoo.com+86 18980601548

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026