meibomian gland dysfunction related dry eye
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Aged 18 to 80 years; 2.According to the diagnostic criteria of "eyelid gland dysfunction and dry eye" in the "expert consensus on clinical diagnosis and treatment of dry eye" formulated by Ophthalmology Society of Chinese Medical Association; 3.Lower lacrimal river height > 0.1mm, meibomian gland obstruction level 1~2; 4.Monocular or binocular lesions; 5.Informed consent and signed informed consent.
Exclusion criteria
Exclusion criteria: 1.Acute ocular surface inflammation and ocular trauma; 2.Steroidal and non-steroidal anti-inflammatory drugs and immunosuppressants are being used; 3.Participate in other medical device trials or drug clinical trials within three months; 4.Women with severe organic diseases, malignant tumors, pregnancy or childbirth; 5.Poor compliance and incomplete information.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| eye redness;the number of meibomian glands;tear film rupture time;corneal fluorescence staining; | — |
Secondary
| Measure | Time frame |
|---|---|
| lacrimal river height measurement;Palpebral margin morphology;Color and structure of lipid layer;Distribution of lipid layer;Thickness of lipid layer;Quality of meibomian gland;Schirmer test; | — |
Countries
China
Contacts
Ophthalmology Department of the Second Hospital of Shanxi Medical University