Duchenne Muscular Dystrophy
Conditions
Interventions
case series:none
Sponsors
Beijing Children's Hospital Affiliated to Capital Medical University
Eligibility
Sex/Gender
Male
Age
3 Years to 18 Years
Inclusion criteria
Inclusion criteria: 1. Criteria for clinical diagnosis (1) Limb weakness or backward motor development (2) Increased creatine kinase (3) Genetic examination confirmed the existence of Dystrophin gene mutation males, and the gene classification was based on the Leiden Muscular Dystrophy Database (http://www.dmd.dl). 2. Entry criteria: (1) 3-18 years old, in line with clinical diagnostic criteria; (2) Join the research voluntarily and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Suffer from known neurological diseases or major diseases other than genetic diseases, which may affect cognition and mental behavior (for example, hypoxic-ischemic encephalopathy, chromosomal disease, epileptic encephalopathy, etc.); 2. Asymptomatic female carriers; 3. The clinical data is not perfect.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intelligence test;ADHD diagnostic criteria (Fourth revised edition of the statistical manual);Autism behavior rating scale (ABC);Emotional behavior scale score;Personal adaptation and role skills scale III score;Modified Hammersmith functional exercise scale score; | — |
Countries
China
Contacts
Public ContactYang Xinying
Beijing Children's Hospital Affiliated to Capital Medical University
Outcome results
None listed